St. Louis Region
Cherokee-Lemp ties a south-city street to brewery history
The Cherokee-Lemp Historic District gives St. Louis a south-city landmark story built around old commercial blocks, the DeMenil home, and Lemp Brewery.
Cherokee-Lemp Historic District gives south St. Louis a place story with buildings close enough to read from the sidewalk.
The City Cultural Resources page places the district between two city landmarks: the DeMenil home from 1849 and the Lemp Brewery from 1862. The same page says most of the 81 structures in the eleven-block district date from the late 1860s to 1915.
Use the city historic-district page and map before treating a building or storefront as part of the district.
That is why Cherokee Street can feel layered. It is a commercial street, but it also sits between mansion, brewery, storefront, and neighborhood history. A person walking it can see how older south-city fabric still shapes today’s blocks.
Where to see it
- Cherokee-Lemp Historic District
Use the City Cultural Resources page for official district context.
References
More from St. Louis City: browse every local note for the county.
Last checked against the sources above: July 16, 2026.